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Clinical trials for Inflammatory Cytokine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    172 result(s) found for: Inflammatory Cytokine. Displaying page 1 of 9.
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    EudraCT Number: 2018-002173-22 Sponsor Protocol Number: 201800406 Start Date*: 2018-12-04
    Sponsor Name:University Medical Center Groningen
    Full Title: Anti-inflammatory effects of tiotropium in patients with stable COPD
    Medical condition: Chronic obstructive pulmonary disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000656-35 Sponsor Protocol Number: 73042 Start Date*: 2020-09-09
    Sponsor Name:Radboud University Medical Centre
    Full Title: The inflammatory response of monocytes and neutrophils to Crystals after Low dose colchicine in patients with coronary artery disease
    Medical condition: Atherosclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002753-11 Sponsor Protocol Number: TofaSTAT17 Start Date*: 2018-01-25
    Sponsor Name:Tampere University Hospital
    Full Title: The effect of tofacitinib on the activity of JAK-STAT pathways in patients with rheumatoid arthritis (RA)
    Medical condition: Rheumatoid arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2005-003854-80 Sponsor Protocol Number: 02B2005 Start Date*: 2006-01-31
    Sponsor Name:Department of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-University
    Full Title: Modulation of the Surgical Inflammatory Response by Etoricoxib: Peripheral versus Central
    Medical condition: Patients with osteoarthritis undergoing elective primary single hip arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-002222-70 Sponsor Protocol Number: Lidobreast Start Date*: 2013-11-15
    Sponsor Name:University Medical Centre St Radboud
    Full Title: Pilot study: Targeting the inflammatory response after breast cancer surgery with lidocaïne and dexamethasone
    Medical condition: Breast cancer patients who undergo surgery for treatment.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-001971-61 Sponsor Protocol Number: SALYCENDO Start Date*: 2016-08-29
    Sponsor Name:Radboudumc
    Full Title: The effects of acetylsalicylic acid on immunoparalysis following human endotoxemia.
    Medical condition: We will investigate the effects of acetylsalicylic acid on immunoparalysis following human endotoxemia in healthy male volunteers
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-005537-30 Sponsor Protocol Number: NL_ABR51923 Start Date*: 2015-06-09
    Sponsor Name:Radboud university medical center
    Full Title: Does ticagrelor modulate the inflammatory respons to human endotoxemia?
    Medical condition: We will study in male healthy volunteers whether ticagrelor modulates the inflammatory response to the administration of lipopolysaccharide (LPS) in humans in vivo.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003018-29 Sponsor Protocol Number: 2016-003018-29 Start Date*: 2017-05-31
    Sponsor Name:Herlev and Gentofte Hospital
    Full Title: Apremilast as anti-pruritic treatment in patients with prurigo nodularis
    Medical condition: Prurigo nodularis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2022-004078-53 Sponsor Protocol Number: 83403 Start Date*: 2023-08-22
    Sponsor Name:Academic Medical Center (AMC), department of Internal Medicine
    Full Title: Specifying the anti-inflammatory effects of ziltivekimab with diverse imaging modalities and in-depth cellular phenotyping
    Medical condition: - Plaque characteristics - Systemic inflammation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000924-14 Sponsor Protocol Number: S52549 Start Date*: 2011-05-23
    Sponsor Name:KU Leuven LRD
    Full Title: Development and validation of a sputum biomarker mRNA panel for the diagnostic work-up of asthma
    Medical condition: asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002273-41 Sponsor Protocol Number: OPHT-110106 Start Date*: 2006-06-12
    Sponsor Name:Medical University of Vienna; Clinical Pharmacology
    Full Title: Effect of antioxidants on ocular blood flow, endothelial function, and cytokine levels in LPS induced inflammatory model in humans.
    Medical condition: only healthy volunteers are involved
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-004974-16 Sponsor Protocol Number: IL1ra03 Start Date*: 2018-11-08
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMISED CLINICAL DOSE-RANGING STUDY TREATING MODERATE-SEVERE TRAUMATIC BRAIN INJURY PATIENTS WITH RECOMBINANT HUMAN INTERLEUKIN 1 RECEPTOR ANTAGONIST.
    Medical condition: We wish to study the drug Kineret in patients suffering from moderate-to-severe traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    20.1 10029205 - Nervous system disorders 10051288 Central nervous system inflammation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006263-23 Sponsor Protocol Number: ML20910 Start Date*: 2006-12-05
    Sponsor Name:ROCHE
    Full Title: Efficacy of Oseltamivir treatment in laboratory- confirmed influenza: evaluation of effect on viral shedding and on serum and cytoplasmatic inflammatory cytokine concentration.
    Medical condition: Influenza type A and B virus infection
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-004938-42 Sponsor Protocol Number: EHRVI Start Date*: 2013-03-01
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Experimental Human Rhinovirus Infection, a randomized placebo-controlled pilot study
    Medical condition: Viral infections in general, and the "common cold" induced by HRV-16 in particular.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10061494 Rhinovirus infection PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2022-003325-22 Sponsor Protocol Number: 2022-15944 Start Date*: 2023-01-25
    Sponsor Name:RadboudUMC
    Full Title: The immunomodulatory effect of sugammadex after total hip replacement surgery under neuraxial anaesthesia: a pilot study
    Medical condition: Hip osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005227-37 Sponsor Protocol Number: OLT1177-10 Start Date*: 2021-03-03
    Sponsor Name:Olatec Therapeutics LLC
    Full Title: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of the Safety and Efficacy of Orally Administered Dapansutrile Capsules for the Treatment of Moderate COVID-19 Symptoms and Evidence of ...
    Medical condition: COVID-19, cytokine release syndrome
    Disease: Version SOC Term Classification Code Term Level
    23.1 10042613 - Surgical and medical procedures 10084460 COVID-19 treatment PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002860-86 Sponsor Protocol Number: 2007/099 Start Date*: 2007-06-26
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The adenosine receptor; a new pharmacological tool in the treatment of sepsis.
    Medical condition: Systemic inflammatory response
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2018-002978-52 Sponsor Protocol Number: CNTO1959HDS2002 Start Date*: 2019-07-16
    Sponsor Name:Universitair Medisch Centrum Groningen
    Full Title: Guselkumab for hidradenitis suppurativa, a mode of action study.
    Medical condition: Hidradenitis suppurativa
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-003755-39 Sponsor Protocol Number: CRx-102-001 Start Date*: 2004-09-29
    Sponsor Name:CombinatoRx, Inc
    Full Title: A SINGLE CENTER, SINGLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED STUDY OF THE EFFECT OF CRx-102 COMPARED TO PLACEBO ON SERUM C-REACTIVE PROTEIN (CRP) AND INFLAMMATORY CYTOKINES IN SUBJECTS WITH SEVERE...
    Medical condition: Severe adult periodontitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000435-13 Sponsor Protocol Number: JWGKDVAAP0117 Start Date*: 2017-11-13
    Sponsor Name:University Hospital Frankfurt for its Dermatology Department, Clinical Research
    Full Title: Exploratory study to evaluate changes in inflammatory pattern and analysis for serum biomarkers in patients with active, moderate-to-severe hidradenitis suppurativa after 2-week and 6-week treatmen...
    Medical condition: Hidradenitis suppurativa is defined as a chronic inflammatory disease of the intertriginous area, including the axilla, groin and anogenital or submammary regions. The condition is characterized by...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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